"The Pope is from Chicago. This is one of the biggest moments in the modern history of our city," said Mayor Brandon Johnson in a statement.

Bishop Thomas John Paprocki of the Diocese of Springfield released a statement expressing profound joy and deep gratitude to God for the election.

Many sites associated with past popes have become museums or holy destinations for the faithful. But Pope Leo XIV’s childhood church closed years ago.

John Prevost, Pope Leo's older brother, confirmed his MLB allegiance in multiple interviews, putting to rest the debate between the North and South Side.

Chicago-born Cardinal Robert Francis Prevost, was chosen as the 267th Pope elected by 133 cardinals locked inside the Sistine Chapel on the second day of their conclave - a process that has been in the cultural zeitgeist recently due to the Oscar-nominated movie of the same name starring Ralph Fiennes.

Sox fans jumped on the news, posting tweets that the Cubs’ claim was premature. If it’s true he’s a Sox fan, Pope Leo XIV would be the team’s second representative of the Vatican after former Sox pitcher “The Pope” Donn Pall.

The church where Pope Leo XIV attended mass as a child and served as an altar boy is now an empty shell.Only the stained glass windows remain intact inside the sturdy facade of St Mary's of the Assumption on the far edge of Chicago's South Side.

Sports fans had one question when Cardinal Robert Prevost of Chicago was elected as the new pope: What are his favorite teams?

Globally, everyone is reacting to the newly-appointed Pope in the Catholic Church, and bishop of Rome. On Thursday, it was announced that Cardinal Robert Prevost has been named the new pope, he is the first American pope in history and will go by the name Pope Leo XIV who was born and raised in Chicago, Illinois.

In an exciting turn of events, the world has its first American Pope, and American flags waved proudly in Vatican City as he addressed the crowd. Meanwhile, in Washington, Reggie Cecchini is diving into the reactions from Americans on this historic moment.